Daunorubicin Metabolism in Acute Myelocytic Leukemia
نویسندگان
چکیده
منابع مشابه
Daunorubicin metabolism in acute myelocytic leukemia.
mic enzyme that converts daunorubicm to a principal metabolite, daunorubicino!, in the presence of NADPH. This enzyme, found in mammalian tissues and studied in rat tissue preparations and normal human blood components, is also present in human leukemic myeloblasts. The enzymes from both normal and leukemic leukocytes require NADPH for activity, have similar kinetics and substrate saturation ch...
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ژورنال
عنوان ژورنال: Blood
سال: 1972
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v39.5.637.637